Saif al-Arab Gaddafi, the youngest son of the Libyan leader, and three of his grandchildren have been killed in a NATO air strike, a Libyan government spokesman said.
Gaddafi and his wife were in the Tripoli house of his 29-year-old son, Saif al-Arab Gaddafi, when it was hit by at least one missile fired by a NATO warplane late on Saturday, according to Libyan government spokesman Moussa Ibrahim.
"The house of Mr Saif al-Arab Gaddafi was attacked tonight with full power. The leader with his wife was there in the house with other friends and relatives.
"The leader himself is in good health, he wasn't harmed," the spokesman said, adding that Muammar Gaddafi's wife was also unharmed but other people in the house were injured.
"This was a direct operation to assassinate the leader of this country. This is not permitted by international law. It is not permitted by any moral code or principle.
"What we have now is the law of the jungle," Ibrahim told a news conference.